Okay, we've never had a client with this problem before and just discovered that on our newest computer, which is not a VISTA computer is having this same trouble. When when put in a slide show to auto play from the CD, it works (auto plays) in all our other machines, but for some reason on the newest machine, it doesn't autoplay. We had a client that came up with this problem as well and her machine is pretty new too. Our newest was purchased last November, but like I said all the other machines (five of them) auto play just fine. Anyone know what the issue might be, because I am stumped. I thought maybe it was that stupid pop up window that comes up when a CD is put in which says, what do you want to do? Who came up with that ingnorant window anyway? It's been nothing but a pain in my butt with these XP machines. I can tell it not to show up ever again, yet it does anyway. Whatever, but that doesn't seem to be the problem because the P2E slide shows autorun on my XP machine fine, just not Randy's machine or this clients unless we go explore the CD and run it manually.